GoDubai
  
  
  
  
Citylife > Press Release
  Home Contact us Add to Favourites
Most Recent Postings
More Press Releses
Featured Sections

Event Finder
A daily roundup of exhibitions, promotions and other events in Dubai and the rest of the Emirates.
Submit an Event
Latest Dubai Press Releases >> Healthcare, Fitness and Medicine

 
  Share

Improved Bone Marrow Transplants, Gene Therapies, and New Medications Will Mean Longer, Healthier Lives for Sickle Cell Disease and Thalassemia Patients, Cleveland Clinic Physician Tells Arab Health Congress

January 31st 2018, DUBAI:   A series of clinical breakthroughs will revolutionize treatment of genetic blood disorders and increase the life expectancy of children diagnosed with sickle cell disease and thalassemia, a leading physician said today during the Arab Health Congress in Dubai.

Dr. Rabi Hanna, M.D., a specialist in pediatric hematology, oncology, and blood and bone marrow transplantation at Cleveland Clinic in the United States, says significant changes in treatment are likely in the next five to ten years, including advances in bone marrow transplant techniques, gene therapies, and improved medications.

Currently, the most common treatments, including blood transfusions and medication, only relieve the symptoms of the disease rather than provide a cure, and many patients will die young. Unless they can receive a bone marrow transplant, the average life expectancy of a child diagnosed with sickle cell disease is just 34 years.

“We really have to provide a cure, and the only cure available has been bone marrow transplantation, with the best outcome from donors who are matched family – brothers and sisters,” Dr. Hanna said, speaking on the sidelines of Arab Health.

“In the past few years there have been big steps forward in haplo-transplants, using family members that are only half-matched, particularly a mum or dad with 50 percent of the child's genes. That will give more children the chance of a cure, replacing bone marrow that is defective with new bone marrow that is healthy.”

New treatments will be particularly important in several Arab countries, where rates of both sickle cell disease and thalassemia are higher than in Europe or North America. 

Both diseases cause abnormalities of the patient's hemoglobin, the part of the red blood cells that transport oxygen.

“For thalassemia, the occurrence is much higher in the Middle East compared with the U.S., and for sickle cell disease it is slightly higher, especially in Saudi Arabia and the United Arab Emirates,” Dr. Hanna said. “For thalassemia, one in every 12 in the United Arab Emirates is a carrier for the gene that causes the disease.”

Dr. Hanna says trials of haplo-transplants are now in phase two and three, testing for efficacy and side-effects. Cleveland Clinic was part of an initial phased study, using modified chemotherapy to help prepare patients.

Gene therapy, using modified DNA to introduce a functional gene to replace the mutated gene causing the blood disorder, offers additional possibilities for a cure beyond bone marrow transplants.

“Early phase one studies looking at this area of gene therapy for thalassemia are very promising, although they are in the very early stages so it's going to take time before we see them become available in a clinical setting,” said Dr. Hanna.

“There are also several medications that have recently been developed for the treatment of sickle cell disease and thalassemia – two have been approved by the FDA, and others are pending. These aren't a cure, but they can make the disease less severe.”

Dr. Hanna was speaking as part of the Pediatrics Conference within the Arab Health Congress, and was one of several Cleveland Clinic physicians sharing their knowledge and experience during the event. Cleveland Clinic is a long-standing partner of Arab Health, and provides Continuing Medical Education accreditation for the congress program.



Posted by : GoDubai Editorial Team
Viewed 14750 times
Posted on : Wednesday, January 31, 2018  
Replication or redistribution in whole or in part is expressly prohibited without the prior written consent of GoDubai.com.
Previous Story : MEDLAB 2018 at the forefront of raising standard of practice and development of better service for p...
Next Story : Emitac brings world's best med-tech solutions to DSO's first hospital project - Fakeeh University Ho...
Email this article Print this article

Share this article with your friends and followers
NewsVine

Comments

Back to Top  
Most Viewed Press Release posted in the last 7 days
Introducing Burberry Bespoke Fragrances
Making many tones from one
Celebrate the Month of Love with a Brighter Smile at The Smile Bar
Longchamp Spring/summer 2019 Show
A Chaumet Valentine's Day Sentimental jewellery
Malabar Gold & Diamonds opens a new showroom in Millennium Dubai Airport Hotel t...
Persil Appoints Nancy Ajram as the new Regional Brand Ambassador
Tissot PRS 516 Alpine Limited Edition A sporting tribute
Global Village presents Scheherazade, a timeless tale of intrigue and adventure
The Preston watch collection by Coach
Turkish Airlines reached the 80.2% Load Factor in December 2018.
Tag Heuer Demonstrates Watchmaking Mastery With Its New Carrera Calibre Heuer 02...
Always take the front row with this 7.2” supersized smartphone screen
Celebrate Valentine's Day With a Quintessential Timepiece From D1 Milano
Eberhard & Co. Gilda makes an extraordinary Valentine's Day gift
Beef Sushi- Love at first bite
Walid Atallah's “Dream Dress”: The new revolution in the World of Fashion 2019
Bollywood Actor Anil Kapoor to inaugurate 2 new outlets of Malabar Gold & Diamon...
Scuderia Ferrari presents PILOTA Family Collection
Third Edition of Al Shira'aa International Horse Show Concludes with Thrilling Finale
HUGO BOSS watches Legacy Casual Family collection
Luxury jewelry house Dhamani 1969 launches exclusive CHRYSALIS collection
Nissan Energy demonstration hits the spot
MALABAR GOLD - DSF Winner Photo for Release - Anandan Ganesh
Nicole Kidman at the Golden Globe Awards
Joyalukkas Shopper wins BMW Car in DSF Mega Promotion
Flying Grand Regulator now available in new colour combinations
Time for Unsung Heroes to Be Recognised With Citizen Campaign
Jewellery shoppers to keep winning big this Dubai Shopping Festival
Al Mouj Muscat pays tribute to Oman with Layers of Oman Exhibition
Spring/Summer ‘19 Collection IL Gufo Underwater
Bollywood Actor Anil Kapoor inaugurated 2 new outlets of Malabar Gold & Diamonds...
The Kingdom of Saudi Arabia's Minister of Energy, Industry, and Mineral Resource...
OMEGA reintroduces the iconic Calibre 321
Sawalef Perfumes unveils product range of delicate scents in 2019
Dubai-based sports star Sarra Lajnef gets Women Leadership Award
Dawoodi Bohra Trade Expo begins at Expo Centre Sharjah
Audi turns the car into a virtual reality experience platform at CES
Citi UAE opens Citigold lounge in Abu Dhabi.
Opening Ceremony of Azerbaijan House in the United Arab Emirates
Alawwal bank becomes first Middle East firm to offer AI training for all staff
The Region's Most Anticipated Shopping Festival Is Back at Burjuman
2020 Cadillac XT6 Makes Global Debut
Central Bank of the UAE Holds its 1st Board of Directors Meeting for 2019
Airbus boosts Intersec 2019 with Progressive Comms Technology
The UAE-Kosovo Economic Forum launches a new phase of economic partnerships
Global Energy Forum: His Excellency Khalid Al-Falih's address on day three
IPAF hosts 10th UAE Nadwa
Sultan Awards Oil & Gas Exploration Concession to Italy's Eni
UAE residents go on a two-week Camel Trek across the UAE desert