GoDubai
  
  
  
  
Citylife > Press Release
  Home Contact us Add to Favourites
Most Recent Postings
More Press Releses
Featured Sections

Event Finder
A daily roundup of exhibitions, promotions and other events in Dubai and the rest of the Emirates.
Submit an Event
Latest Dubai Press Releases >>

 
  Share

13 February 2018, Dubai, UAE:   This International Childhood Cancer Day, paediatric haematologist expert, Professor Ajay Vora, from Great Ormond Street Hospital in London (GOSH) discusses how advances in cellular therapy are set to revolutionise treatment for children with acute lymphoblastic leukaemia (ALL). 

Acute lymphoblastic leukaemia (also called ALL or acute lymphocytic leukaemia) is a cancer of the blood and bone marrow.  Leukaemia is one of the ten most common malignancies in Saudi Arabia, Kuwait and UAE, and a major form of paediatric cancer. In the UAE, a recent study found a high rate of ALL (32%) among males. 

According to Professor Vora, childhood leukaemia outcomes have improved in the past four decades, with 90% of children with ALL surviving. These improvements in outcomes have also translated for children in the Middle East as well. 

“There are a number of new pioneering treatments being developed at GOSH to treat leukaemia using immune cells, and some of these are being tested in clinical trials”, explains Prof. Vora. “These treatments are experimental and are only considered when routine chemotherapy treatments haven't worked. A Kuwaiti patient will soon be the first international patient to receive CAR-T cell therapy at GOSH.”

CAR-T cell therapy, a type of cellular therapy currently being trialled at GOSH to treat ALL, involves collecting a patient's own white blood cells (or immune cells) and modifying them so they can attack specific cancers.

“One major issue, especially in infants, is the difficulty in collecting enough of the right type of immune cells (T cells)”, Prof. Vora explains. “For such cases, new approaches are being tested that use T cells from a healthy donor but are modified using ‘gene-editing' so they don't need to be matched to the patient. This means the cells are ‘universal' and can be produced in advance and stored frozen, ready to be used in multiple patients.” 

The gene-edited T cells (called UCART19) are given to patients immediately after a course of chemotherapy and antibody therapy. They are expected to circulate around the body and fight any leukaemia carrying the CD19 marker. Responses are assessed after one month, and if remission had been achieved, the patient will proceed to have a bone marrow transplant. At that stage the cells are removed and do not persist long-term.

This innovative treatment is currently available at GOSH as part of its research trials, and will become available in the near future to patients from across the world once the research phase is over. 

“Cellular therapy has the potential to revolutionise the treatment of leukaemia in children. Currently, it provides a chance to treat patients who have failed to respond to other treatment. If further research confirms preliminary data on efficacy, in future, it will provide a less toxic alternative to haemopoietic stem cell transplantation,” Prof. Vora concludes.

GOSH, who treats 1,500 children from the Middle East every year, has treated 271 haematology patients between April – Dec 2017.

 



Posted by : GoDubai Editorial Team
Viewed 10297 times
Posted on : Tuesday, February 13, 2018  
Replication or redistribution in whole or in part is expressly prohibited without the prior written consent of GoDubai.com.
Previous Story : Arianna Huffington calls for a Third Women's Revolution to redesign a world focused on Augmented Hum...
Next Story : WGS 2018: Mindfulness Is an Awareness of the Here and Now, Emphasizes Stress Management Expert
Email this article Print this article

Share this article with your friends and followers
NewsVine

Comments

Back to Top  
Most Viewed Press Release posted in the last 7 days
D1 Milano Launches Exlcusive Limited Edition Collection –The Khaleeji
Beware of Cheap Beauty Deals: They May End Up Being More Costly
8 Jours Grande Taille - a new avatar on iconic timepiece
Get Ready for The Festive Season with The Body Shop's Enchanted by Nature Gift C...
Tissot Lady Heart Flower Powermatic 80
Sukin's Top Holiday Picks for a Supple-Skin Winter Season
Switch your hair colour safely for the new season with Rahua's Color Full range
Everyday care for your baby's hair with Fifi & Friends!
Omega Raises Its Warranty On All Watches to 5 Years
Bringing you warmth and shine this festive season
Season's Greetings 2018
Twelve Holiday Gifts for the Beauty-Obsessed Woman
The Smile Bar Opens Its First Store in the UAE
Purely Pandora Classics With a Twist
Chloé Eyewear's Feminine Appeal Seen Through the Lens of the New “Rosie” Style
New 1948 Seamaster Watches Join the Ranks
Festive Gifting Guide
Add a festive sparkle to your eyes with Palladio Beauty
The Geo-Graham Orrery Tourbillon presents a galaxy you can reach out and wear Ge...
Tryano Launches Elemis
Amp up your skincare routine with The Organic Pharmacy's new corrective serums
#MKGO Bold: Michael Kors Unveils Bold New Arrivals
Triumphant First Daman Dxb Swimfest at Jumeirah Beach Hotel
Hour Choice presents Coach Park Collection
Parmigiani Fleurier, new Friends of the Brand – ice-hockey superstar, Evgeniy Ma...
Certina DS PH200M collection
Indulge Your Love for Animal Print with M&S
Parah dedicates its Fall/Winter 2018/19 collection to femininity
Joyalukkas brings joy to hundreds around the world with gold bar giveaway this f...
Starbucks announces the return of festive favourites
Coca-Cola Puts Extra Fizz Into Its Factory Thanks to Digitisation
National Geographic Launches Mars 2 into Orbit with Season 2 Premiering Nov 15 ...
Give an abandoned or neglected cat their forever home at Kittysnip's adoption da...
Land Rover Supports Red Cross Disaster Projects Worldwide
The new BMW 8 Series Convertible.
Introducing the GUESS Holiday 2018 Collection
Sawalef Perfumes is now available at Mirdif City Centre
Sprint for a Great Cause at Al Maha
‘Celebrate 2019 Now' with special deals from Al-Futtaim Toyota
Etihad Airways Launches Model Diary of Xiaowen at China International Import Expo
LACOSTE presents its new Legacy collection
Department of Culture and Tourism – Abu Dhabi Organises ‘Herfaty' Programme in A...
Jameel Arts Centre, Dubai opens with an ambitious set of exhibitions and program...
Tissot T-Race Marc Marquez
Unilever MENA calls for collective action as it's revealed that 54% of consumers...
The Sharjah Stamp Exhibition celebrates the Year of Zayed
Superhero Color Runners Prove We Are All Unstoppable!
IKEA Promises 25 Years of Quality Guarantee
Top five new things to do at Golden Mile Galleria this season
Bharat Thakur Artistic Yoga's Flagship Studio opens in Burjuman.